Reduced time to market and decreased production costs by improving productivity are central issues in pharmaceutical bioprocessing. Within this context the combined application of Process Analytical Technology (PAT) tools and reliable but also flexible bioprocess equipment is the basis for an efficient automation and optimization of existing production processes as well as the development of new ones. A key element to achieve process knowledge for both continuous and batch processes is a fast and easily, understandable feedback of information from the process data to the engineers and operators in the plant. Multivariate batch modeling empowers the extraction and presentation of information in real-time, to efficiently secure high process quality with essential savings for the industry. Focusing on fast feedback the next logical step is multivariate feed forward and feed backward closed loop control. The presentation will deliver application examples and cases from the biopharmaceutical industry.